WebJul 20, 2024 · To the best of our knowledge, this is the first report showing molecular details underlying formation of the MPP1-flotillin complex that opens a new outlook in our … WebApr 4, 2024 · Antibodies targeting the flotillin-1/2 complex have been described in 1-2% of the patients in a recent study. Other candidate antigens as anoctamin-2 or neurofascin-155 have been previously described in multiple sclerosis patients, although their clinical relevance remains uncertain. Our study aims to analyse the frequency and clinical ...
Proteomic comparison defines novel markers to characterize ...
WebFeb 9, 2024 · Using site-specific mapping, we also uncovered that the SPFH (stomatin, prohibitin, flotillin, and HflK/C) domain of flotillin-1 interacted with TRPV2 N-termini and transmembrane domains 1-4, respectively. Our findings therefore demonstrate that flotillin-1 is a key element in TRPV2 signaling complex and modulates its cellular response. WebFlotillin-mediated endocytosis and ALIX–syntenin-1–mediated exocytosis protect the cell membrane from damage caused by necroptosis Weiliang Fan1,2, ... for the cross-linking and tandem affinity purification of the lipid raft–bound phospho-MLKL protein complex. TSZ, TNF (20 ng/ml), Smac mimetic (100 M), and z-VAD (20 M); DSP, dithiobis ... daft punk the game of love
Flotillin-1 (D2V7J) XP® Rabbit mAb Cell Signaling Technology
WebMar 2, 2012 · We here show that flotillin-1 forms a complex with CRAF, MEK1, ERK, and KSR1 (kinase suppressor of RAS) and that flotillin-1 knockdown leads to a direct … WebJun 15, 2024 · Here, we report for the first time about a 65-year-old woman presenting with a dementia combined with serum autoantibodies against flotillin-1/2 complex connected mainly to the plasma membrane … WebA protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae. Source: … daft punk the prime time of your life