WebOct 12, 2024 · Background and Aims: Diagonal earlobe crease (ELC) has been considered a potential cutaneous marker of atherosclerosis. However, the potential mechanism by which ELC and atherosclerosis are linked has not been adequately defined. Roles of adropin and irisin, novel biomarkers of endothelial function, in ELC have not been well-studied. WebOct 17, 2024 · We investigated the frequency and clinical significance of diagonal earlobe crease (DELC) in cognitively impaired patients using imaging biomarkers, such as white …
Bilateral Earlobe Creases and Coronary Artery Disease
WebNov 2, 2011 · The diagonal ear-lobe crease, a physical sign associated with coronary heart disease. Acta Med Scand Suppl. 1978;619:1-49. 10. Wermut W, Jaszczenko S, Ruszel A. Ear lobe crease as a risk factor in coronary disease. Wiad Lek. 1980;33(6):435-438. 11. Fisher JR. Sievers ML. Ear-lobe crease in American Indians. WebJul 25, 2024 · Frank’s sign was defined as a bilateral, diagonal crease in the ear lobe extending from the tragus across the lobule to the rear edge of the auricle. Before the … cheetah football team
Frank’s Sign: An Indicator for Premature Aging?
WebNov 1, 2024 · Usually, the crease runs diagonally from your ear canal to the outer edge of your earlobe. Studies have linked the presence of diagonal earlobe creases to clogged arteries. WebSep 20, 2024 · Frank’ sign or diagonal earlobe crease (DELC) is a diagonal earlobe crease that extends backwards from the tragus at an angle of 45 degree across the lobule to the ear edge of the auricle. It has been described as a dermatological marker for coronary artery disease. Frank’s sign is a useful clinical sign for coronary artery disease. WebJun 25, 2024 · Diagonal earlobe crease, a wrinkle extending obliquely across the earlobe, was linked by many authors to various atherosclerotic diseases. This systematic review aimed at summarizing the diagnostic accuracy of diagonal earlobe crease for diagnosis of chronic and acute coronary syndromes in adults. Cochrane's recommendations for … fleece lined utility jacket