Webcontaining the complete CYP3A4 and CYP3A7 gene sequences, in-cluding 5 - and 3 -flanking sequence (Fig. 1A), was identified. The BAC clone was purified by using a maxiprep kit (QIAGEN, Valencia, WebCYP3A7 is an enzyme belonging to the cytochrome P450 family. It is 503 amino acids in size and shares 87% of its sequence with CYP3A4. It carries out a similar role in fetuses that CYP3A4 serves in adults.[5] The gene location is 7q22.1.[6] CYP3A7 is an enzyme belonging to the cytochrome P450 family.
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WebCYP3A4, CYP3A5, and CYP3A7, which are located in a multigene locus (CYP3A), play crucial roles in drug metabolism. To understand the highly variable hepatic expression of CYP3As, regulatory network analyses have focused on transcription factors (TFs). Since long non-coding RNAs (lncRNAs) likely contribute to such networks, we assessed the … WebThe CYP3A7*1Cpromoter reporter gene was strongly activated by CAR, in contrast to the lack of activation of the CYP3A7 reporter (Fig.7 B). Mutation of only the ER6 motif in the CYP3A7 promoter to CYP3A4-ER6 was not, however, sufficient to achieve a significant increase in activation by CAR, whereas the reciprocal mutation in the CYP3A4 promoter ... is strategery a real word
DGIdb - CYP3A7 Gene Record
WebMar 21, 2024 · CYP3A7 (Cytochrome P450 Family 3 Subfamily A Member 7) is a Protein Coding gene. Diseases associated with CYP3A7 include Myopathy, Centronuclear, 4 and Neonatal Abstinence Syndrome . Among its related pathways are Oxidation by … CYP1A2 (Cytochrome P450 Family 1 Subfamily A Member 2) is a Protein … CYP2D6 (Cytochrome P450 Family 2 Subfamily D Member 6) is a Protein … ALOX5 (Arachidonate 5-Lipoxygenase) is a Protein Coding gene. Diseases … CYP3A5 (Cytochrome P450 Family 3 Subfamily A Member 5) is a Protein … CYP4B1 (Cytochrome P450 Family 4 Subfamily B Member 1) is a Protein … WebMar 21, 2024 · Complete information for lnc-CYP3A7-2 gene (RNA Gene), , including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium WebCYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation. The rs776746 variant of CYP3A5 is associated with intravenous midazolam plasma levels and higher clearance in critically ill Mexican paediatric patients. ifor homes